DFG Priority Program SPP 1258: Sensory and regulatory RNAs in Prokaryotes
Detection of novel ncRNAs in prokaryotes and investigation of structural/functional features within them, as well as analysis of the interaction between bacterial ncRNAs and their target mRNAs.
Small non-coding RNAs (ncRNAs) in bacteria provide another layer to regulate gene expression. The main problems in this context are the detection of ncRNAs and the prediction of the mRNA targets. We develop a system to detect novel ncRNAs and investigate structural/functional features within them. Secondly, we analyse the interaction between bacterial ncRNAs and their target mRNAs.
Project description - http://www.bioinf.uni-freiburg.de/Research/dfg-spp-1258.html
Chair for Bioinformatics - http://www.bioinf.uni-freiburg.de/