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SFB 604 - Project B10: Alternative splicing as a modulator of signal transduction

Multifunctional signalling proteins harbour many protein domains. These can be varied by alternative splicing, a mechanism, how genomic blueprints can be converted into different transcripts. We will predict and analyse new splice variants and apply new machine learning approaches such as Bayesian networks.

We want to gain more insight into the processes involved in the regulation of alternative splicing and in the regulation by alternative splicing. We will apply this knowledge to selected multifunctional proteins and protein complexes studied within the framework of the SFB. For more details, please visit the project homepage.

 

Project description - http://www.bioinf.uni-freiburg.de/Research/sfb604.html

Project web site - http://www.sfb604.uni-jena.de/Project_B10.html

Chair for Bioinformatics - http://www.bioinf.uni-freiburg.de/

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