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BMBF Project D.6

Alternative splicing at NAGNAG acceptors result in the insertion/deletion (indel) of 3 nt into the transcript.

We observed found non-NAGNAG splice sites with EST evidence for such a 3 nt indel. Since SNPs influence alternative NAGNAG splicing, we hypothesize that these acceptors have a NAGNAG motif in another allele. The respective ESTs might be sampled from cells having such a NAGNAG allele. The goal of this project is investigate the reason for the observed tiplet indels and to use these events to predict and verify new SNPs.

 

Project description - http://www.bioinf.uni-freiburg.de/Research/bmbf-jcb-d6.html?de

Chair for Bioinformatics - http://www.bioinf.uni-freiburg.de/

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